Calprotectin: Non-invasive Gold Standard for the Diagnosis of Bowel Inflammation

Only a small proportion of patients with abdominal discomfort have an organic disease, but a correct diagnosis can rarely be made by simple clinical examination. The acute phase protein calprotectin (MRP 8/14) allows the discrimination between organic and functional intestinal diseases. Calprotectin is excreted in excess in stool during inflammatory bowel disease (IBD) but not during inflammatory bowel syndrome (IBS). It is therefore an important tool in the differential diagnosis of bowel irritations and plays a key role in monitoring disease activity in patients with chronic inflammations.

Article from November 11, 2009

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