Qualitative detection of human IgG antibodies against SARS-CoV-2 in serum or plasma
Sars-CoV-2 - or formerly 2019-nCoV, "2019 novel corona virus" - is the name of a virus identified at the turn of the year 2019/2020 in the Chinese province of Wuhan. The virus causes COVID-19 (corona virus disease 2019), a respiratory disease. The disease spreads via droplet infection and has been detected in the secretions of the nose and throat, sputum, tear fluid and stool. (Detection of the virus: via PCR)
The incubation period can be up to 14 days. Infection of other people is possible already during the incubation period - even if persons are free of symptoms. Likewise, there is an explicit risk of spreading in the case of a subjectively asymptomatic course. The symptoms may be fever, dry cough and muscle pain, sometimes also general fatigue and diarrhoea. In severe cases, pneumonia may develop or intensive medical care may be required.
Since the courses of the disease are very different and the virus is very infectious, it is not sufficient to isolate only clinically conspicuous individuals for quarantine measures. Here, or for epidemiological studies, it is useful to test not only for the presence of the virus, but also for IgM or IgG antibodies against SARS-CoV-2 in the course of a suspected COVID-19 disease.
IgG antibodies are - after the IgM immune response of the body - the most produced immunoglobulins in the body in response to the viral antigen and serve as a long-term proof of an infection with SARS-CoV-2 and a passed COVID-19 infection.
The ELISA is specific for human IgG antibodies directed against SARS CoV-2 antigen and contains a positive and negative control.
The human plasma or serum sample (10 µl) has to be diluted 1:100 in the IgG sample dilution buffer for the test; 2 x 100 µl of this dilution are used for the double determination in the ELISA.
Coronavirus COVID-19 IgG ELISA Kit KKT1032
In vitro diagnostic agent for the determination of IgG antibodies against SARS-CoV-2 in plasma and serum.
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