β2-Microglobulin (β2-M) ELISA
Plasma, Serum, Urine
b-2-Microglobulin is a light chain protein (11.8 kD) of the HLA-class-I antigens and is found on the cell membrane of all nucleated cells. This protein is metabolised extensively in the kidney. The serum concentration is influenced by the rates of synthesis and metabolism and is usually stable in healthy persons. Changes in the serum concentrations are indicative of disorders in glomerular and tubular functions.