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PMN-Elastase (IDK® PMN-Elastase) (1-point-calibration) (Stool) ELISA
Article number:
K 6830
Tests:
96 Tests
Incubation time:
3 x 1 h; 5-20 min
Volume:
15 mg
Matrix:
Stool
Standards:
0.37-10 ng/ml
Method:
ELISA
This ELISA Version (K 6830) is based on a 1-point-calibration.
PMN-Elastase from human polymorphnuclear granulocytes is a glycoprotein of 30 kDa and belongs to the group of serine proteases. Active PMN-Elastase is released from azurophil granula of neutrophil granulocytes after irritation or disintegration. The determination of the PMN-Elastase in stool is used to record inflammatory reactions where neutrophils are involved. Especially in Crohn´s disease the inflammatory process go hand in hand with an increased phagocytic activity and the biological decay of these cells and thus leads to an increased release of PMN-Elastase and other lysosomal enzymes.
PMN-Elastase from human polymorphnuclear granulocytes is a glycoprotein of 30 kDa and belongs to the group of serine proteases. Active PMN-Elastase is released from azurophil granula of neutrophil granulocytes after irritation or disintegration. The determination of the PMN-Elastase in stool is used to record inflammatory reactions where neutrophils are involved. Especially in Crohn´s disease the inflammatory process go hand in hand with an increased phagocytic activity and the biological decay of these cells and thus leads to an increased release of PMN-Elastase and other lysosomal enzymes.
