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Relaxin ELISA
Article number:
K 9210
Tests:
96 Tests
Incubation time:
o. n. (16-22 h); 2 h; 1 h; 20-30 min
Volume:
100 µl
Matrix:
Serum, Plasma, Urine, Seminal plasma, Tissue
Standards:
3.1-250 pg/ml
Method:
ELISA
For further information please visit Relaxera Website.
Relaxin belongs to the insulin family and was originally described as a hormone produced in the ovaries, which was mainly detectable during pregnancy and birth. However, latest investigations have shown, that synthesis of relaxin could also occur in the placenta, endometrium, mammary glands, or prostata. The binding of relaxin to specific receptors has been observed in the brain, uterus and the heart, which speaks in favour for the multi-functionality of this hormone. In the first animal models (rat) relaxin functions as a strong chronotropic and inotropic agent in normotensive as well as in spontane hypertensive rats. The mechanisms, which lead to the increase in heart frequency and promote contractions of the heart muscles, are still unclear. The effects were however stronger in comparison to angiotensin II and it is assumed that this effect is mediated via specific receptors in the heart.
Relaxin belongs to the insulin family and was originally described as a hormone produced in the ovaries, which was mainly detectable during pregnancy and birth. However, latest investigations have shown, that synthesis of relaxin could also occur in the placenta, endometrium, mammary glands, or prostata. The binding of relaxin to specific receptors has been observed in the brain, uterus and the heart, which speaks in favour for the multi-functionality of this hormone. In the first animal models (rat) relaxin functions as a strong chronotropic and inotropic agent in normotensive as well as in spontane hypertensive rats. The mechanisms, which lead to the increase in heart frequency and promote contractions of the heart muscles, are still unclear. The effects were however stronger in comparison to angiotensin II and it is assumed that this effect is mediated via specific receptors in the heart.
