<< Back
Thymosin ß4 ELISA
Article number:
Incubation time:
1 h, 1 h, 10-20 min
50 µl
Serum, Thymus extract
0.16-10 µg/ml
Details (PDF)
To access these files, you need the Acrobat Reader
For research use only.
The beta-thymosins are a family of highly conserved polar 5 kDa peptides originally thought to be thymic hormones. Further studies demonstrated that the molecule is ubiquitous; it had been found in a variety of tissues and cell lines. It is found in highest concentrations in spleen, thymus, lung, and peritoneal macrophages. Thymosin beta 4 binds monomeric actin in a 1:1 complex and act as actin buffers, preventing polymerization into actin filaments but supplying a pool of actin monomers when the cell needs filaments. Changes in the expression of thymosin beta 4 appear to be related to the differentiation of cells. Thymosin beta 4 is detected outside of cells in blood plasma or in wound fluid. Several biological effects are attributed to thymosin beta 4, like induction of metallo-proteinases, chemotaxis, angiogenesis and inhibition of inflammation as well as the inhibition of bone marrow stem cell proliferation.

Purchase Order Processing

Claudia Wandesleben / Gudrun Gutschalk
Phone: +49 6251 70190-175 /-177
Fax: +49 6251 70190-363
email: export@immundiagnostik.com

Contact Form Order Form