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Thiol-Status (Sulfhydryl-Status Test) photometric
K1800, 1800
Article number:
K 1800
Tests:
96 Tests
Incubation time:
30 min
Volume:
20 µl
Matrix:
Serum, Plasma, Urine, Synovia
Standards:
one point calibration
Method:
photometric
Details (PDF)
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Serum protein thiol levels in blood are a direct measure of the in vivo reduction/oxidation (redox) status in humans, because thiols react readily with oxygen-containing free radicals to form disulfides. Moreover, serum thiols also reflect DNA repair capacity and the possible eventual accumulation of genetic damage, since a key DNA repair enzyme, poly ADP-ribose polymerase (PARP), is thiol/disulfide redox regulated.
Serum protein thiols can possibly be used to estimate individual aging status. Data from Banne AF et al. (2003, Anti Aging Med 6:327-34) strongly confirm an important role of oxidative stress in human disease development, and identify serum thiol status as a potential biochemical endpoint useful in the assessment of aging.

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