Pregnenolone sulfate LC-MS/MS

Article number: YM2000

Test-Category

LC-MS/MS

Pack size

100 Tests

Possible sample matrix and volumes

Plasma 50 µl
Serum 50 µl

Indications

Regulatory Status

CE marked outside EU: RUO (research use only)

Pregnenolone sulfate LC-MS/MS is for the LC-MS/MS based quantification of pregnenolone sulfate in human serum and plasma after precipitation reaction. The assay is an in vitro diagnostic medical device for manual or automatic use by professional laboratory staff in a laboratory environment. The assay serves as an aid in monitoring pregnenolone sulfate-dependent physiological states in endocrine or neurological disorders.

Test principle
A precipitation reaction is used for pregnenolone sulfate enrichment. After chromatographic separation, the analyte is measured via tandem mass spectrometry (MS/MS) in multiple reaction monitoring (MRM) mode.
A stable isotope-labelled version of the analyte is used as internal standard to compensate variances during the sample preparation and matrix effects.