Relaxin ELISA

Article number: K 9210

Test-Category

ELISA

Pack size

96 Tests

Standard concentrations included in the kit

3.1-250 pg/ml

Possible sample matrix and volumes

Serum 100 µl
Plasma 100 µl
Urine 100 µl
Seminal plasma 100 µl
Tissue 100 µl

Incubation periods

  1. Over night
  2. 2 hours
  3. 1 hour
  4. 20-30 minutes

Indications

Regulatory Status

CE marked

For further information please visit www.relaxera.de

Relaxin belongs to the insulin family and was originally described as a hormone produced in the ovaries, which was mainly detectable during pregnancy and birth. However, latest investigations have shown, that synthesis of relaxin could also occur in the placenta, endometrium, mammary glands, or prostata. The binding of relaxin to specific receptors has been observed in the brain, uterus and the heart, which speaks in favour for the multi-functionality of this hormone. In the first animal models (rat) relaxin functions as a strong chronotropic and inotropic agent in normotensive as well as in spontane hypertensive rats. The mechanisms, which lead to the increase in heart frequency and promote contractions of the heart muscles, are still unclear. The effects were however stronger in comparison to angiotensin II and it is assumed that this effect is mediated via specific receptors in the heart.