PerOx (TOS/TOC) (Oxidative Capacity), colorimetric

Article number: KC5100

Test-Category

Miscellaneous

Test-Method

colorimetric

Pack size

96 Tests

Standard concentrations included in the kit

one point calibration

Possible sample matrix and volumes

EDTA plasma 20 µl
Serum 20 µl

Incubation periods

  1. 15 minutes

Indications

Regulatory Status

CE marked

An overproduction of oxygen radicals or insufficient antioxidative capacity leads to a dangerous imbalance in the organism. This starts pathological mechanisms which develop several diseases. The most important disease is the cardiovascular arterosclerosis. Beside this inflammation processes, sepsis, cancerogenesis and neurodegenerative diseases are postulated.
This is the reason why the determination of the oxidative status/oxidative stress is of fundamental importance in medical diagnosis and in research. The methods used for measurement of radical-linked effects (lipid peroxidation) up to now are very time consuming (HPLC) or reflect only breakdown products of multiple unsaturated fatty acids (TBARS).
The PerOX-Assay is fast, reliable and easy to perform. Total lipidperoxides are measured. Because of a direct correlation between oxygen radicals and lipidperoxides it is possible to measure and characterize the oxidative status/oxidative stress in biological fluids.