MutaPLEX® Coronavirus real time RT-PCR kit

MutaPLEX® Coronavirus real time RT-PCR kit


For the simultaneous in vitro detection of RNA of novel coronavirus (SARS-CoV-2) and other betacoronaviruses, extracted from biological specimens, especially throat swabs and sputum.

The test also has a systemic control based on the human ß-actin gene: only by (separate) amplification of this gene the correct and sufficient sample collection from the patient is proven.

Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). The novel Corona¬virus (SARS-CoV-2) is a new strain that has been previously identified in humans and causes the pulmonary disease COVID-19.
Coronaviruses are zoonotic, meaning they are transmitted between animals and people. Detailed investigations found that SARS-CoV was transmitted from civet cats to humans and MERS-CoV from dromedaries to humans. Several known coronaviruses are circulating in animals that have not yet infected humans.
Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death.
Standard recommendations to prevent infection spread include regular hand washing - soapy water destroys the lipid structures of the virus - covering mouth and nose when coughing and sneezing, sneezing into the crook of the arm, avoiding close contact with anyone showing symptoms of respiratory illness or are known to have tested positive for SARS-CoV-2.
The MutaPLEX® Coronavirus (SARS-CoV-2) real time RT-PCR Kit is a screening assay for the simultaneous detection of RNA of novel coronavirus (SARS-CoV-2) and other Beta-coronaviruses (e.g. MERS-CoV, SARS-CoV) extracted from biological specimens. In addition to the human ß-actin gene as a control for the clinical starting material, the test also contains an extraction control detecting errors in sample preparation and also potential PCR inhibition!

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