IDK® Calprotectin (MRP 8/14) (Stool) ELISA

Article number: KR6927

Test-Category

ELISA

Pack size

96 Tests

Standard concentrations included in the kit

13-840 ng/ml

Possible sample matrix and volumes

Stool 15 mg

Incubation periods

  1. 30 minutes
  2. 30 minutes
  3. 10-20 minutes

Indications

Regulatory Status

outside EU: RUO (research use only)

Calprotectin is a calcium binding protein, expressed in neutrophils and monocytes. Fecal Calprotectin is a marker for inflammatory and neoplastic gastrointestinal diseases. The differentiation between patients with irritable bowel syndrome and inflammatory bowel diseases (IBD) is often difficult and leads to unnecessary coloscopies. Our IDK® Calprotectin ELISA enables the differential diagnosis in these two patient groups. The determination of Calprotectin in stool correlates very well with histological and endoscopic parameters of disease activity in Morbus Crohn and Colitis ulcerosa. In contrast to previous standard markers of inflammation (e.g. CRP, ESR, HB), an elevated Calprotectin-level is a superior indicator for relapse. Therefore, Calprotectin is an ideal marker for therapy monitoring in IBD patients. The parameter exhibits a high negative predictive value: If the Calprotectin-level in stool is low, there is a high likelihood that there is no inflammatory organic disease in the intestinal tract.

IDK® Calprotectin ELISA (K 6927):

  • Monclonal test system
  • Cut-off at 50 µg/g
  • Incubation: only 2 x 30 min
  • Ready-to-use conjugate
  • Broad measurement range up to 2100 µg/g
  • Also available as 1-point calibration assay (K 6967)