Thymosin ß4 ELISA

Article number: KR9520



Pack size

Standard concentrations included in the kit

0.16-10 µg/ml

Possible sample matrix and volumes

Serum 50 µl
Thymus extract 50 µl

Incubation periods

  1. 1 hour
  2. 1 hour
  3. 10-20 minutes


Regulatory Status

RUO (research use only)

The beta-thymosins are a family of highly conserved polar 5 kDa peptides originally thought to be thymic hormones. Further studies demonstrated that the molecule is ubiquitous; it had been found in a variety of tissues and cell lines. It is found in highest concentrations in spleen, thymus, lung, and peritoneal macrophages. Thymosin beta 4 binds monomeric actin in a 1:1 complex and act as actin buffers, preventing polymerization into actin filaments but supplying a pool of actin monomers when the cell needs filaments. Changes in the expression of thymosin beta 4 appear to be related to the differentiation of cells. Thymosin beta 4 is detected outside of cells in blood plasma or in wound fluid. Several biological effects are attributed to thymosin beta 4, like induction of metallo-proteinases, chemotaxis, angiogenesis and inhibition of inflammation as well as the inhibition of bone marrow stem cell proliferation.