IDK® EDN (1-point-calibration) ELISA

Article number: K 6821

Test-Category

ELISA

Pack size

96 Tests

Standard measuring range

0.25-16 ng/ml

Possible sample matrix and volumes

Serum 20 µl
Plasma 20 µl
Urine 20 µl
Stool 15 mg

Incubation periods

  1. 1 hour
  2. 1 hour
  3. 10-20 minutes

Indications

Regulatory Status

CE marked

EDN (eosinophil-derived neurotoxin, eosinophil protein x, EPX), a cationic glycoprotein, which is released by activated eosinophiles, has strong cytotoxic characteristics and plays a significant role in the prevention of virus infections. It is released by the eosinophile granules in places where eosinophiles are mainly found, in the skin, lungs, urogenital, gastrointestinal tract, that is, in the organs which act as an entry point for pathogens. The accumulation of EDN in the intestine is associated with tissue damage.
Measuring EDN in stool can serve as an objective parameter for a current clinical or sub-clinical cronic inflammation which is located in the gastrointestinal area. In the case of Colitis ulcerosa and Crohn's disease, the EDN measurement enables the evaluation of a disease activity and the prediction of a relapse.

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