IDK® sIgA (secretory Immunglobulin A) ELISA

Article number: K 8870

Test-Category

ELISA

Pack size

96 Tests

Standard concentrations included in the kit

22.2-600 ng/ml

Possible sample matrix and volumes

Saliva 10 µl
Stool 15 mg

Incubation periods

  1. 1 hour
  2. 1 hour
  3. 10-20 minutes

Indications

Regulatory Status

CE marked not for sale in the US

Secretory IgA (sIgA) is an immunoglobulin formed by plasma cells located in the lamina propria. sIgA plays a crucial role in the immune function of the mucosa. It serves as a first line of defence of the mucous membranes against pathogenic germs, enteric toxins and food allergens. In healthy people, sIgA covers the mucosa in a protective layer and therefore occurs in body secretions.
Determining sIgA concentrations in stool provides information about the activation and secretion rate of the intestinal plasma cells located in the lamina propria, thus allowing to draw conclusions about the status of the immunological barrier of the intestinal mucosa.